NAPLEX (North American Pharmacist Licensure Examination) Practice Exam 2026 - Free NAPLEX Practice Questions and Study Guide

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When giving a live vaccine, how should it be timed with a TB skin test to avoid a false negative?

Live vaccine and skin test 4 weeks apart

Live vaccine and skin test on the same day

Get skin test first then live vaccine 48-72 hours later

Any of the above methods

Timing of live vaccines and TB skin tests is not critical, as long as the live vaccine is given on a different day than the skin test. Option A suggests that there should be a 4-week gap between the vaccine and skin test, which is not necessary. Option B suggests getting the vaccine and skin test on the same day, which is not recommended as it may interfere with the skin test results. Option C suggests getting the skin test first and then the live vaccine 48-72 hours later, which is also not necessary as it may lead to a false positive for the skin test. Therefore, option D, which states that any of the above methods can be used, is the correct answer.

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