NAPLEX (North American Pharmacist Licensure Examination) Practice Exam 2025 - Free NAPLEX Practice Questions and Study Guide

Question: 1 / 1820

Which medication combination is NOT recommended for moderate emetic risk?

NK1-RA + 5HT3-RA + Dexamethasone

5HT3-RA + Dexamethasone

5HT3-RA + Corticosteroids

The medication combination that is NOT recommended for moderate emetic risk is 5HT3-RA + Corticosteroids (Choice C). This is because for moderate emetic risk, the preferred regimen typically involves using a 5HT3 receptor antagonist in combination with a neurokinin-1 receptor antagonist (NK1-RA) and dexamethasone (Choice A). This triple combination provides a comprehensive antiemetic effect.

While 5HT3-RA + corticosteroids (Choice C) may be effective in preventing nausea and vomiting, it is not the preferred combination for moderate emetic risk when compared to the triple therapy of NK1-RA + 5HT3-RA + dexamethasone (Choice A).

The other options can be ruled out as they are not the standard therapy for moderate emetic risk.

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Palonosetron + Olanzapine + Dexamethasone

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