NAPLEX (North American Pharmacist Licensure Examination) Practice Exam 2026 - Free NAPLEX Practice Questions and Study Guide

Phenylephrine and Pseudoephedrine are both decongestants commonly used in over-the-counter cold and allergy medications. However, recent FDA guidelines suggest avoiding these medications in children under the age of 2 due to potential side effects such as increased heart rate and blood pressure. While Oxymetazoline is also a decongestant, it is not explicitly mentioned in the FDA guidelines for children under 2. Therefore, the safest option for children under 2 would be to avoid both Phenylephrine and Pseudoephedrine altogether.