NAPLEX (North American Pharmacist Licensure Examination) Practice Exam 2026 - Free NAPLEX Practice Questions and Study Guide

5HT-3 RAs (5-Hydroxytryptamine-3 receptor antagonists) are a type of medication used to treat nausea and vomiting. Serotonin is a chemical in the brain that can affect appetite, mood, and other bodily functions. Therefore, it is important to understand the side effects of 5HT-3 RAs and identify which option is NOT a possible side effect.

Option A Increased appetite, while it may seem like a possible side effect due to the association with serotonin, is not a known side effect of 5HT-3 RAs. It is important to note that some people may experience increased appetite while on this medication, but it is not a common or predicted side effect.

Option B: Headache is a common side effect of 5HT-3 RAs, as they can affect the levels of serotonin in the brain. However, it is still a recognized side effect and not the correct answer for this question.

Option C: Constipation is a possible side effect of 5HT-3 RAs. These medications can affect the digestive system, slowing down bowel movements and potentially causing constipation.

Option D: Serotonin syndrome is a serious condition caused by an excess of serotonin