NAPLEX (North American Pharmacist Licensure Examination) Practice Exam 2026 - Free NAPLEX Practice Questions and Study Guide

Medication Overuse Headaches (MOH), also known as rebound headaches, occur when someone uses headache medications too frequently. This causes a cycle where the headaches initially disappear but then return, leading to increased medication use and worsening of the headaches. This makes B the correct answer because the overuse of headache medications, or any medication for that matter, can lead to MOH. Option A and C are incorrect because while sleep disturbances and memory loss can be side effects of some headache medications, they are not the result of overuse. Option D is also incorrect because there is no evidence that overuse of headache medications increases appetite.