NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Prepare for the NAPLEX (North American Pharmacist Licensure Examination) Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

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For which type of antibiotics is the goal to maintain drug level greater than MIC for most of the dosing interval?

Concentration dependent antibiotics
Exposure dependent antibiotics
Time dependent antibiotics
none of the above

The correct answer is: Time dependent antibiotics

Time dependent antibiotics are those that require a prolonged duration of time where the concentration of the drug is maintained above the minimum inhibitory concentration (MIC). The goal is to maintain the drug level above MIC for most of the dosing interval, not just for a short period of time like in concentration dependent antibiotics. Exposure dependent antibiotics depend on achieving a certain level of drug exposure rather than maintaining a specific level for a certain length of time. None of the above is incorrect because time dependent antibiotics are the correct answer.