NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Prepare for the NAPLEX (North American Pharmacist Licensure Examination) Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

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Vortioxetine's dose should be decreased by what percentage when used with strong CYP2D6 inhibitors?

25%
50%
75%
100%

The correct answer is: 50%

When vortioxetine is used with strong CYP2D6 inhibitors, the dose should be decreased by 50%. This is because strong CYP2D6 inhibitors can increase the concentration of vortioxetine in the body, leading to a higher risk of adverse effects. Therefore, reducing the dose by 50% helps to maintain the therapeutic efficacy of the medication while minimizing the likelihood of side effects. Options A, C, and D are incorrect because they do not reflect the appropriate percentage by which the vortioxetine dose should be decreased when used with strong CYP2D6 inhibitors.