NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Prepare for the NAPLEX (North American Pharmacist Licensure Examination) Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

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What is the risk when warfarin levels increase due to CYP2C9 inhibitors?

  1. Liver damage

  2. Increased blood pressure

  3. Bleeding risk

  4. Kidney failure

The correct answer is: Bleeding risk

When warfarin levels increase due to CYP2C9 inhibitors, the risk involved is an increased bleeding risk. Warfarin is an anticoagulant medication used to prevent blood clots, and its effectiveness is highly dependent on maintaining the appropriate therapeutic levels in the body. CYP2C9 inhibitors can interfere with the metabolism of warfarin, leading to higher levels of the medication in the body, which can increase the risk of bleeding complications such as bruising, gastrointestinal bleeding, or hemorrhage. Option A, liver damage, is not directly associated with an increase in warfarin levels due to CYP2C9 inhibitors. Option B, increased blood pressure, is not a typical consequence of elevated warfarin levels. Option D, kidney failure, is also not a known risk of increased warfarin levels due to CYP2C9 inhibitors. The primary concern when warfarin levels rise due to CYP2C9 inhibitors is the potential for an elevated bleeding risk.