NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which is not a method of comminution?

  1. Levigation

  2. Spatulation

  3. Coating

  4. Trituration

The correct answer is: Coating

Comminution refers to the process of reducing the size of solid particles into smaller pieces. Levigation, spatulation, and trituration are all methods of comminution used in pharmacy practice. Levigation involves grinding a powder along with a liquid to form a smooth paste, spatulation involves mixing and grinding using a spatula, and trituration involves grinding a substance with a mortar and pestle. On the other hand, coating is not a method of comminution; it refers to the process of applying a thin layer of a different material onto the surface of a solid particle to achieve specific properties such as taste masking, protection, or controlled release.