NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which medication is a combination of Metformin and sitagliptin?

  1. Janumet

  2. Glargine

  3. Levemir

  4. Tresiba

The correct answer is: Janumet

Janumet is the correct answer. Janumet is a combination medication that contains both Metformin and sitagliptin. Metformin is a biguanide medication used to treat type 2 diabetes by decreasing glucose production in the liver and improving insulin sensitivity. Sitagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the release of insulin and decreasing the amount of glucose produced by the body. Combining these two medications in Janumet provides a dual mechanism of action to help control blood sugar levels in patients with type 2 diabetes. The other options, Glargine, Levemir, and Tresiba, are long-acting insulin analogs used to manage blood sugar levels in patients with diabetes, but they do not contain Metformin or sitagliptin.