NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

Disable ads (and more) with a membership for a one time $2.99 payment

Prepare for the NAPLEX (North American Pharmacist Licensure Examination) Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Start Multiple Choice Practice Test
Start Flash Cards

Each practice test/flash card set has 50 randomly selected questions from a bank of over 500. You'll get a new set of questions each time!

Practice this question and more.

Which medication is known to inhibit T and B lymphocyte proliferation by altering purine nucleotide synthesis?

  1. Mycophenolate mofetil

  2. Azathioprine

  3. Both Mycophenolate mofetil and Azathioprine

  4. Tacrolimus

The correct answer is: Both Mycophenolate mofetil and Azathioprine

Both Mycophenolate mofetil and Azathioprine are known to inhibit T and B lymphocyte proliferation by altering purine nucleotide synthesis. Mycophenolate mofetil inhibits the enzyme inosine monophosphate dehydrogenase, which is important in purine synthesis. Meanwhile, Azathioprine is converted to 6-mercaptopurine, which also affects the production of purine nucleotides. Tacrolimus, on the other hand, works by inhibiting the production of cytokines and has a different mechanism of action compared to Mycophenolate mofetil and Azathioprine.

More Questions Like This