NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Prepare for the NAPLEX (North American Pharmacist Licensure Examination) Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

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Which NRTI is known for causing hyperpigmentation of palms/soles?

  1. Lamivudine (Epivir)

  2. Zidovudine (Retrovir)

  3. Emtricitabine

  4. Tenofovir disoproxil fumarate (Viread)

The correct answer is: Emtricitabine

Emtricitabine is the correct answer. Emtricitabine is known for causing hyperpigmentation of palms and soles as a side effect. This adverse effect is important to recognize when prescribing or dispensing this medication to patients. Lamivudine (option A) and Tenofovir disoproxil fumarate (option D) are not typically associated with hyperpigmentation of palms and soles. Zidovudine (option B) is known for causing a different side effect, which is bone marrow suppression, rather than hyperpigmentation of palms and soles.