NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Prepare for the NAPLEX (North American Pharmacist Licensure Examination) Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

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Which of the following should NOT be used with Mavyret due to contraindications?

Efavirenz
Magnesium supplements
Acetaminophen
Sodium bicarbonate

The correct answer is: Efavirenz

Mavyret is a medication used to treat chronic hepatitis C infection. It is a combination of two drugs, glecaprevir and pibrentasvir. Efavirenz is a medication used to treat HIV infection, and it should not be used with Mavyret due to potential drug interactions which may decrease the effectiveness of Mavyret. Magnesium supplements are not contraindicated with Mavyret, but they may cause unwanted side effects when taken together, such as diarrhea or stomach pain. Acetaminophen and sodium bicarbonate are also not contraindicated with Mavyret, however, it is important to always consult with a healthcare provider before taking any medications, including over-the-counter ones, while on Mavyret. This is because they may potentially interact with the medication and its effectiveness or safety may be affected. Therefore, the option that should not be used with Mavyret due to contraindications is A.